VTPP Faculty Member - TIMOTHY A. CUDD, D.V.M., Ph.D.

TIMOTHY A. CUDD, D.V.M., Ph.D.

Associate Professor

Email: tcudd@cvm.tamu.edu

EDUCATION:

D.V.M., Veterinary Medicine, University of Tennessee, 1982

Ph.D., Physiology, University of Florida, 1992

Postdoctoral Training: Fetal Physiology, University of Florida, 1994

PREVIOUS EMPLOYMENT:

Assistant Research Scientist, Department of Physiology, College of Medicine, University of Florida
Assistant Professor, Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine

HONORS:

Phi Eta Sigma
American Association of Equine Practitioners Pediatrics Committee
International Society of Veterinary Perinatology Editorial Committee
Grinter Scholar, College of Veterinary Medicine, University of Florida
International Society of Veterinary Perinatology Secretary/Treasurer
International Society of Veterinary Perinatology Board Member
Second International Veterinary Perinatology Conference
College of Veterinary Medicine Resident and Graduate Student Annual Research Award
President of the International Society of Veterinary Perinatology
Research Peer Review Committee, American Heart Association
Invited Speaker, P.D. Rossdale International Workshop on Equine Perinatology

FUNDED RESEARCH (last 3 years):

Reflex cardiovascular and hormonal responses to thromboxane (American Heart Association: Florida Affiliate Grant in Aid $75,321)
Central hemodynamic and hormonal actions of thromboxane A2 (American Heart Association, Texas Affiliate Grant-in-Aid $83,561)
Lung influence on fetal development and parturition (American Lung Association, Texas Affiliate $50,000)
Ovine model system for alcohol related birth defects (National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, RO1 $895,929)

PROFESSIONAL SOCIETIES:

American Heart Association, Basic Science Council

American Physiological Society

American Veterinary medical Association

International Society of Veterinary Perinatology

Research Society on Alcoholism

CURRENT RESEARCH SUPPORT:

National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, RO1, "Ovine model system for alcohol related birth defects", T.A. Cudd, P.I., $895,929 Total Costs.

National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, RO3 "Fatty acid ethyl esters in sheep meconium". C.F. Bearer, P.I., T.A. Cudd, Collaborator, $44,928 Total Costs.

PAST RESEARCH SUPPORT:

American Heart Association: Florida Affiliate, Postdoctoral Fellowship "Influence of prostaglandin E₂ on the control of cardiovascular function by the fetal brain", $57,000.

American Heart Association: Florida Affiliate Grant in Aid, T.A, Cudd P.I. "Reflex cardiovascular and hormonal responses to thromboxane", $75,321.

American Heart Association, Texas Affiliate Grant-in-Aid, Central hemodynamic and hormonal actions of thromboxane A₂, T.A. Cudd, P.I., $83,561.

American Lung Association, Texas Affiliate, ?Lung influence on fetal development and parturition, T.A. Cudd, P.I., $50,000 Total Costs.

Center for Environmental and Rural Health, "Birth defects arising in early development Alcohol/nutritional interactions", T.A. Cudd, P.I., $17,700.

Texas A&M University, Collge of Veterinary Medicine Signature Program Funding, "Training grant in cardiovascular pathophysiology" P.I.s: G Laine, J Wasser, T Cudd, J Stallone, A. Knowlton, $80,000 Total costs.

PROFESSIONAL SOCIETIES:

American Heart Association, Basic Science Council
American Physiological Society
American Veterinary medical Association
International Society of Veterinary Perinatology
Research Society on Alcoholism

ACADEMIC APPOINTMENTS AND PROFESSIONAL EXPERIENCE:

Veterinarian, Woodford Veterinary Clinic, PO Box 108, Versailles, Kentucky 40383.

Veterinarian, Rood and Riddle Equine Hospital, 2150 Georgetown Road, Lexington, Kentucky 40511.

Predoctoral associate, Department of Physiological Sciences, College of Veterinary Medicine, University of Florida.

American Heart Association Florida Affiliate Research Fellow, Department of Physiology, College of Medicine, University of Florida.

Postdoctoral associate, Department of Physiology, College of Medicine, University of Florida.

Assistant research scientist, Department of Physiology, College of Medicine, University of Florida.

Assistant professor, Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine, Texas A&M University.

Associate Professor, Department of Veterinary Physiology & Pharmacology, College of Veterinary Medicine, Texas A&M University.

SELECTED RESEARCH PUBLICATIONS:

Cudd, T.A., Wood, C.E. Does intracarotid PGE₂ increase plasma ACTH concentration in conscious adult ewes? Am. J. Physiol. 261 (Endocrinol. Metab. 24): E395-E401, 1991.
Cudd, T.A., Wood, C.E. Prostaglandin E₂ releases ovine fetal ACTH from a site not perfused by the carotid vasculature. Am. J. Physiol. 263 (Regulatory, Integrative Comp. Physiol.32) : R136-R140, 1992.
Cudd, T.A., Wood, C.E. Prostanoid cascade inhibition prevents the cardiovascular and adrenocortropic responses to mineral acid infusion in conscious sheep. Am. J. Physiol. 264 (Regulatory, Integrative Comp. Physiol. 33): R1235-R1241, 1993.
Wood, C.E., Kane, C., Engelke, K., Cudd, T.A. Fetal ACTH and blood pressure responses to thromboxane mimetic U46619. Am. J. Physiol. (Regulatory, Integrative Comp. Physiol. 34): R858-R862, 1993.
Cudd, T.A., Castro, M.I., Wood, C.E. Content, in vivo release and bioactivity of fetal pulmonary immunoreactive adrenocorticotropin. Am. J. Physiol. (Endocrinol. Metab. 28): E667-E672, 1993.
Cudd, T.A., Castro, M.I., Wood, C.E. Content, in vivo release and bioactivity of fetal pulmonary immunoreactive adrenocorticotropin. Am. J. Physiol. (Endocrinol. Metab. 28): E667-E672, 1993.
Cudd, T.A., Wood, C.E. Thromboxane A₂ receptor antagonism prevents the hormonal and cardiovascular responses to mineral acid infusion. Am. J. Physiol. (Regulatory, Integrative Comp. Physiol. 36): R1235-R1240, 1994.
Cudd, T.A., LeBlanc, M., Silver, M., Norman, W., Madison, J., Keller-Wood, M., Wood, C.E. Ontogeny and ultradian rhythms of adrenocorticotropin and cortisol in the late gestation fetal horse. J. Endocrinol., 144: 271-283, 1995.
Cudd, T.A., Wood, C.E. Secretion and clearance of immunoreactive ACTH by fetal lung. Am. J. Physiol. (Endocrinol. Metab.31): E845-E848, 1995.
Cudd, T.A., Wood, C.E. Does thromboxane A₂ mediate the fetal ACTH response to acidemia? Am. J. Physiol. (Regulatory, Integrative Comp. Physiol. 39): R594-R598, 1996.
Cudd, T.A., Chen, W.-J.A., West, J.R. Acute hemodynamic and adrenocortical responses to alcohol in adult female sheep. Alcohol. Clin. Exp. Res. 20:1675-1681, 1996.
Cudd, T.A., Castellon, R., Purinton, S.C. Thromboxane A₂ acts at a site perfused by the carotid vasculature to mediate cardiovascular and adrenocortical responses. Can. J. Physiol. Pharmacol. 75:271-278, 1997.
Wood, C.E., Purinton, S., Cudd, T.A. Immunoreactive thromboxane synthase is measurable in ovine fetal hypothalamus as early as 86 days’ gestation. Prostaglandins 54: 569-579, 1997.
Cudd, T.A. Thromboxane A₂ does not act at the carotid sinus to mediate cardiovascular, adrenocorticotropin, cortisol or blood gas responses. Can. J. Physiol. Pharmacol. 76: 118-124, 1998.
Cudd, T.A. Thromboxane A₂ acts on the brain to mediate hemodynamic, adrenocorticotropin and cortisol responses. Am. J. Physiol. (Regulatory, Integrative Comp. Physiol.) 274: R1353-1360, 1998.
Cudd, T.A., Purinton, S., Patel, N. and Wood, C.E. Protective hemodynamic and hormonal actions of hypertonic saline in euvolemic sheep are altered prostaglandin synthase inhibition. Shock 10: 32-36, 1998.
Wood, C.E, Barkoe, D., The, A., Newman, H., Cudd, T.A., Purinton, S. and Castro, M.I. Fetal pulmonary immunoreactive adrenocorticotropin: Molecular weight and cellular localization. Regulatory Peptides 73:191-196, 1998.
Cudd, T.A. Vagal blockade does not prevent adrenocorticotropin, cortisol and cardiopulmonary responses to thromboxane A₂. Can. J. Physiol. Pharmacol. 76:1087-1094, 1998.
Keller-Wood, M., Cudd, T.A., Norman, W., Caldwell, S.M., Wood, C.E. A model in sheep for the study of maternal adrenal function during pregnancy. Lab. Animal Sci. 48:507-512, 1998.
Cudd, T.A. and Wasser, J.S. Biomedical device design discovery team approach to teaching physiology to undergraduate bioengineering students. Am. J. Physiol. 277 (Adv. Physiol. Educ. 22): S29-S41, 1999.
Cudd, T.A., Wasser, J.S., Chen, W.-J.A., West, J.R. Brain high energy phosphate responses to ethanol exposure in neonatal rats: an in vivo ³¹P-NMR study. Alcohol. Clin. Exp. Res. 24:865-872, 2000.
Cudd, T.A., Chen, W.-J.A., Parnell, S.E., West, J.R. Third trimester binge alcohol exposure results in fetal hypercapnea and acidemia but not hypoxemia in pregnant sheep. Alcohol. Clin. Exp. Res. 25:269-275, 2001.
West, J.R., Parnell, S.E., Chen, W.-J. A., Cudd, T.A. Alcohol-mediated Purkinje cell loss in the absence of hypoxemia during the third trimester in an ovine model system. Alcohol. Clin. Exp. Res. 25:1051-1057, 2001.
Cudd, T.A., Chen, W.-J.A., Parnell, S.E., West, J.R. Fetal and maternal sheep hypothalamus pituitary adrenal axis responses to chronic binge ethanol exposure during the third trimester equivalent. Alcohol. Clin. Exp. Res. 25: 1065-1071, 2001.
Cudd, T.A., Chen, W.-J.A., Parnell, S.E., West, J.R. Fetal and maternal thyroid hormone responses to ethanol exposure during the third trimester equivalent of gestation in sheep. Alcohol. Clin. Exp. Res. 26: 1065-1071, 2002.