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Publications

  • Ramaiah SK and Rittling S.  Pathophysiological role of osteopontin in liver inflammation, toxicity and cancer.  Toxicologic Sciences, Epub ahead of print 2007. pdf
  • Ramaiah SK and Rittling, S.  Role of osteopontin in regulating hepatic inflammatory responses and toxic liver injury.  Expert Opin Drug Metab Toxicol. 3: 519-526, 2007..
  • Ramaiah, SK. A toxicologist guide to the diagnostic interpretation of hepatic clinical pathology parameters.  Food. Chem. Toxicol. 45: 1551–1557, 2007.
  • *Ramaiah, SK., and Jaeschke, H. Hepatic neutrophil infiltration in the pathogenesis of alcohol-induced liver injury.  Toxicol. Mechanisms. Methods.  17: 431-440, 2007.
  • Rose, R., Banerjee, A., and Ramaiah, SK.   Characterization  of  a  LPS-mediated neutrophilic hepatitis model  in Sprague Dawley rats.  J. Applied Toxicology, 27, (Epub ahead of print), 2007 .
  • Ramaiah SK and Jaeschke, H.  Role of neutrophils in the pathogenesis of acute inflammatory liver injury.  Toxicol. Pathol. 35:757-66, 2007.pdf
  • Cho, SD, Sudhakar C, Abdelrahim, M., Lei, P., Hamilton, S., Khan, S., Ramaiah, SK and Safe, S.  Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor dependent and independent pathways. Cancer Research, 67: 674-83,  2007.
  • Chintharlapalli, S., Papineni, S., Ramaiah SK., and Safe, S.  Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors.  Cancer Research, 67: 2816-23, 2007.
  • Rose, R., Banerjee, A., and Ramaiah, SK.  Calpain inhibition attenuates iNOS production and midzonal hepatic necrosis in a repeat dose model of endotoxemia in rats.  Toxicologic Pathology 34:  785-794, 2006.
  • Banerjee, A., Burghardt, R., Johnson, G., White, F., and Ramaiah, SK.  The temporal expression of osteopontin (SPP1) in the rodent model of alcoholic steatohepatitis: A potential biomarker.  Toxicologic Pathology. 34: 373-384, 2006.
  • Banerjee, A., Apte, UM., Smith III, R., and Ramaiah, SK. Higher neutrophil infiltration mediated by osteopontin is the likely contributing factor for increased susceptibility of females to Alcoholic Liver Disease.  J. Pathology.  208: 473-85, 2006. 
  • Chintharlapalli,  S. Burghardt,, R., Papineni,  S.,  Ramaiah,  SK,  Yoon, K. and Safe,  S.  Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl) methanes induces apoptosis through nuclear pathways.  Journal of Biol. Chem.  280: 24903-14, 2005.
  • Apte, UM., Banerjee, A., McRee, R., Wellberg, E., and Ramaiah, SK. Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis, Toxicol. Appl. Pharmacol. 207: 25-38, 2005.
  • Apte, U. M., McRee, R., and Ramaiah, SK. Hepatocyte proliferation is the possible mechanism for the transient decrease in liver injury during steatosis stage of alcoholic liver disease. Tox. Path.  32: 567-576, 2004.
  • Ramaiah , SK., Rivera, C., and Arteel, G.  Early phase alcoholic liver disease: Pathology, pathogenesis and animal models.  Internat. J. Toxicol.  23: 217-231, 2004.
  • Ramaiah, SK., Harvey, J., Gigure, S., and Franklin, R. Intravascular hemolysis associated with liver failure concurrent to neutrophil hypersegmentation in the horse. J. Vet. Int. Med, 17, 360-363,2003.
  • Apte, U. M., Limaye, P., Ramaiah, SK., Vaidya SV., Bucci, TJ., Warbritton, A and Mehendale HM. Upregulated signaling via cytokines and growth factors is the mechanism of robust liver tissue repair in thioacetamide-induced hepatotoxicity in caloric restricted rats.  Toxicol. Sci. , 69: 448-459, 2002.
  • Ramaiah, SK, and Alleman AR. Liver cytology: Aspirations and limitations.  Compendium, 24, 798-810, 2002.
  • Ramaiah, SK., Seguin, A., Carwile, H., and Raskin, R.  Biclonal gammopathy associated with  immunoglobulin A in a dog with multiple myeloma.  Vet. Clin. Path. 31: 83-89, 2002. (Highlighted in Cover Page)
  • Ramaiah, SK., Alleman R., Hanel, R., and Uhl, E. A mass in the ventral neck of a hypercalcemic dog.  Vet. Clin. Path. 30: 177-179, 2002.
  • Ramaiah, SK., Apte, U., and Mehendale, HM. Cytochrome P4502E1 increases thioacetamide liver injury in diet restricted rats. Drug Metab. Disp. 29: 1088-95, 2001.
  • *Lock, B., Heard, D., Dunmore, D., and Ramaiah, SK. Lymphosarcoma with a leukemic blood profile in an Aruba Island Rattlesnake.  J. Herpet. Med. Surg. 11: 19-23, 2001.
  • Ramaiah, SK., Apte, U and Mehendale, HM.  Diet restriction and non-cancer end-points of toxicity: A review.  Internat. J. Toxicol. 19: 413-424, 2000.
  • Soni, M.G., Ramaiah, SK., Mumtaz, M., Clewell, H., and Mehendale, HM. Toxicant-inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. Reg. Pharmacol and Toxicol. 29: 165-174, 1999.
  • Ramaiah, SK., Soni, MG., Bucci, TJ., and Mehendale, HM. Diet restriction enhances compensatory liver tissue repair and survival following administration of lethal dose of thioacetamide. Toxicol. Appl. Pharmacol. 150: 12-21, 1998. (Awarded Best Paper in Toxicology and Applied Pharmacology from the Board of Publications, 1999).
  • Ramaiah, SK., Bucci, TJ., Soni, MG., Warbritton, A., and Mehendale, HM.  Temporal  changes in tissue repair permit survival of diet restricted rats from an acute lethal dose of  thioacetamide: Mechanism for survival.  Toxicol. Sciences 45: 233-241, 1998.

Manuscripts Under Review:

  • Banerjee A., Jayaraman, A and Ramaiah, SK.  Identification of novel proteins to predict the molecular basis for the observed gender susceptibility in a rat model of alcoholic steatohepatitis by 2-D gel proteomics.  Proteomics 2007 (Submitted).
  • Ramaiah SK. Identification of liver toxicity by “Good-Old” clinical pathology biomarkers.  Internat. J. Toxicol.  (submitted), 2007.

BOOK CHAPTERS/EDITORIAL:

  1. Ramaiah, SK., and Nabity, M.  Toxicology of the blood and bone marrow.  In:  Veterinary Toxicology: Basic and Clinical Principles (Ed. Gupta, R), Chapter 10, 1st edition, pp 277-288, Elsiever, USA, 2007
  2. Bischoff, K and Ramaiah SK.  Liver Toxicology.  In :  Veterinary Toxicology: Basic and Clinical Principles (Ed.  Gupta, R), Chapter 17, 1st edition, pp 145-160, Elsiever, USA. 2007
  3. Ramaiah, SK, Liver cytology cases in Self Assessment Color Review of Veterinary Cytology (dog, cat, horse and cow) Ed. Freeman, K, Manson Publishing Press, in press, 2007.
  4. Ramaiah, SK., and Mehendale, HM. Monograph on Adiponitrile. In:  Encyclopedia of Toxicology   (Ed.  Philip Wexler), 2nd edition, Oxford,  ISBN 0-12-745354-7, pp 49, 2005.
  5. Ramaiah, SK., and Mehendale, HM. Monograph on Coke oven emissions. In:  Encyclopedia of Toxicology   (Ed.  Philip Wexler), 2nd edition, Oxford,  ISBN 0-12-745354-7, pp 635, 2005.
  6. Ramaiah SK.  Comparative Pharmacokinetics: Principles, Techniques and Applications by Jim Riviere.  Invited comments on book reviews.  JAVMA, 225, 1851, 2004
  7. Ramaiah, SK., and Mehendale, HM. Monograph on Adiponitrile. In:  Encyclopedia of Toxicology   (Ed.  Philip Wexler), 1st  edition, Academic Press,  pp 28, 1998.
  8. Ramaiah, SK., and Mehendale, HM. Monograph on Coke oven emissions. In:   Encyclopedia of Toxicology   (Ed.  Philip Wexler), 1st edition,  Academic Press, pp 357, 1998.

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