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EPI Research

What is EPI?

Exocrine Pancreatic Insufficiency (EPI) is a digestive disorder that most frequently affects the German Shepherd Dog. EPI occurs when the acinar cells of the pancreas are degraded and may be referred to as pancreatic acinar atrophy (PAA). Normally, acinar cells secrete digestive enzymes that help break down food for nutrient absorption. Dogs with EPI are not able to digest their food and show symptoms of starvation, including weight loss, loose stools, and increased appetite. Once diagnosed, enzyme supplements can be given with each meal to aid in food digestion.

You can help!

We are working to identify the gene(s) responsible for EPI. For our research, we need blood and serum samples from unrelated, purebred German Shepherd Dogs that have been diagnosed with EPI. If you would like to participate, please contact Dr. Leigh Anne Clark at lclark@cvm.tamu.edu or for more information visit the EPI Research Fund website or www.epi4dogs.com.

Basko was found at an animal shelter in April of 2004. He only weighed 64lbs and was low in spirit. Upon adoption, he was diagnosed with EPI and started on enzyme supplements. He gained weight rapidly and reached his current weight of 82 lbs in 7 months. By dividing his food into 3 small meals per day to aid digestion, and through the great care of his veterinarian, he is able to live an active life and will be celebrating his 11th birthday in 2008.

"EPI Research"