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DM Research

What is DM?

Degenerative myelopathy (DM) is a progressive, neurodegenerative disorder that is common in large breed dogs, particularly the German Shepherd Dog. Onset of DM usually occurs in dogs 5 to 14 years old. Affected dogs will begin to drag their legs and exhibit other signs of weakness in the hind limbs. Currently, there is no defined diagnostic procedure or treatment regimen for DM. Most affected dogs are euthanized within one year of diagnosis. The cause of DM is unknown and very few studies have been conducted to understand the genetics underlying the disease.

Samples needed!

We are working to identify the genes responsible for DM. For our research, we need blood and serum samples from unrelated, purebred German Shepherd Dogs that have been diagnosed with DM. If you would like to participate, please contact Dr. Leigh Anne Clark at lclark@cvm.tamu.edu.

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